bIn people who were new to or had not failed on biologic therapy.
cThese results came from studies that included people who failed on other medicines or did not tolerate those medicines well. This included biologic medicines.
Learn more about PYZCHIVA, an FDA-approved alternative to Stelara® (ustekinumab)
Why choose PYZCHIVA?Although they are not exactly the same, you can think of a biosimilar as being like a generic medicine. Like generics, biosimilars can be used in place of a name-brand medicine because they deliver results that are just as safe and effective. As a biosimilar to Stelara®, PYZCHIVA can be used in place of Stelara®.
PYZCHIVA is an FDA-approved biosimilar to Stelara® (ustekinumab). This means PYZCHIVA has been thoroughly studied and proven to be as safe and effective as Stelara®. It also means PYZCHIVA can be used in place of Stelara®. PYZCHIVA is FDA approved to treat Crohn's disease, ulcerative colitis, plaque psoriasis, and psoriatic arthritis. Please see full uses for PYZCHIVA below.
The FDA approved PYZCHIVA because it is proven to have the same effectiveness, safety, and quality as Stelara®. This means you can expect the same results with PYZCHIVA as Stelara®.
PYZCHIVA has the same dosing schedule as Stelara®, so switching is straightforward.
Sandoz One Source offers a number of support services to people taking PYZCHIVA, including a Co-Pay Program, access to Case Managers, 1:1 injection support, and more.
PYZCHIVA delivers results for people with different autoimmune conditions. Individual results may vary. Please see full uses for PYZCHIVA below.
bIn people who were new to or had not failed on biologic therapy.
cThese results came from studies that included people who failed on other medicines or did not tolerate those medicines well. This included biologic medicines.
bIn people who were new to or had not failed on biologic therapy.
cThese results came from studies that included people who failed on other medicines or did not tolerate those medicines well. This included biologic medicines.
PYZCHIVA is also FDA approved for children with plaque psoriasis who are aged 6-17. This means it has been proven to be safe and effective in children of these ages. Your child’s doctor can help you decide if PYZCHIVA is the right treatment for them.
PYZCHIVA is also FDA approved for children with plaque psoriasis who are aged 6-17. This means it has been proven to be safe and effective in children of these ages. Your child’s doctor can help you decide if PYZCHIVA is the right treatment for them.
aBased on clinical studies with Stelara®. Only you and your doctor can decide if PYZCHIVA is right for you. Individual results may vary.
Before your first injection, you should talk with your doctor about how to administer PYZCHIVA. Additional injection training and support is available through Sandoz One Source. For complete information on how to inject PYZCHIVA, please see the Instructions for Use in the full Prescribing Information.
Whether you’re starting or switching to PYZCHIVA®, our team is here to help at every step
PYZCHIVA Co-pay Terms and Conditions: Limitations apply. Valid only for those with private commercial insurance. Prescription must be for an approved indication. Restrictions, including monthly and/or annual maximums may apply. Patient is responsible for any costs once program limit is reached. Program not valid (i) if prescription for PYZCHIVA is paid, in whole or in part, under Medicare (including Part D, even in the coverage gap), Medicaid, Medigap, TRICARE, VA, DoD, or any other federal or state health care program, (ii) where patient is not using insurance coverage at all, (iii) where the patient's insurance plan reimburses for the entire cost of the drug, or (iv) where product is not covered by patient's insurance. The value of this program is exclusively for the benefit of patients and is intended to be credited towards patient out-of-pocket obligations and maximums, including applicable co-payments, coinsurance, and deductibles. It is a violation of the terms and conditions of this program to use it to enroll patients for the purposes of a copay accumulator or maximizer program. Sandoz reserves the right to take any appropriate action against any person or entity using the program in violation of the terms and conditions. Program is not valid where prohibited by law. Patient may not seek reimbursement for the value received from this program from other parties, including any health insurance program or plan, flexible spending account, or health care savings account. Patient is responsible for complying with any applicable limitations and requirements of their health plan related to the use of the Program. Valid only in the United States and US Territories (Puerto Rico, Guam, Northern Mariana Islands, and Virgin Islands). This Program is not health insurance. Program may not be combined with any third-party rebate, coupon, or offer. Proof of purchase may be required. Co-pay program has no cash value. Additional terms and conditions may apply. Sandoz reserves the right to rescind, revoke, or amend the Program and discontinue support at any time without notice.
Call 1-855-SANDOZ-8 (1-855-726-3698) to speak with a Sandoz One Source Case Manager
eNurses do not provide medical advice. Please discuss therapy with your healthcare provider.
A biosimilar is a type of biologic medicine. Although they are not exactly the same, you can think of a biosimilar as being like a generic medicine. Like generics, biosimilars can be used in place of a name-brand medicine because they deliver results that are just as safe and effective.
PYZCHIVA is a biosimilar to Stelara® (ustekinumab). There are no differences between PYZCHIVA and Stelara® when it comes to safety, effectiveness, and quality. This means you can expect the same results with PYZCHIVA that you experience with Stelara®.
Yes. PYZCHIVA is an FDA-approved biosimilar, which means it was thoroughly studied before being presented to the FDA. This proved that there are no differences between PYZCHIVA and Stelara® when it comes to safety, effectiveness, and quality.
When it comes to symptom relief, safety, and quality, you can expect the same experience with PYZCHIVA that you’ve had with Stelara®.
PYZCHIVA is a biosimilar to Stelara®. There are no differences between PYZCHIVA and Stelara® when it comes to safety, effectiveness, and quality. This means you can expect the same results with PYZCHIVA that you experience with Stelara®.
However, medicines like PYZCHIVA, are not for everyone; only your doctor can decide if PYZCHIVA is right for you.
PYZCHIVA is a prescription medicine that affects your immune system. It can increase your chance of having serious side effects including serious infections, cancer, serious allergic reactions, lung inflammation, and a rare condition called posterior reversible encephalopathy syndrome.
These are not all the possible side effects of PYZCHIVA. Please read the Important Safety Information located at the bottom of the screen and the Medication Guide for PYZCHIVA to learn more about these and other risks for PYZCHIVA. Discuss any questions you have with your doctor.
In clinical studies, the most common side effects were:
These are not all of the possible side effects of PYZCHIVA. Tell your doctor about any side effect that you experience. Call your doctor for medical advice about side effects.
You should not receive a live vaccine while taking PYZCHIVA. Before receiving PYZCHIVA, tell your doctor if you have recently received or are scheduled to receive an immunization (vaccine). Tell your doctor if anyone in your house needs a vaccine. The viruses used in some types of vaccines can spread to people with a weakened immune system, and can cause serious problems. You should not receive the BCG vaccine during the one year before taking PYZCHIVA or one year after you stop taking PYZCHIVA.
Sandoz One Source is committed to offering support for people who have been prescribed PYZCHIVA. Services such as Case Managers, a Co-Pay Program, and injection support help make the process of starting or switching to PYZCHIVA simple. Learn more about services from Sandoz One Source.
With the PYZCHIVA Co-Pay Program, eligible people with commercial insurance may pay as little as $0 for their treatment. Click below to see the full Terms and Conditions.d
PYZCHIVA Co-pay Terms and Conditions: Limitations apply. Valid only for those with private commercial insurance. Prescription must be for an approved indication. Restrictions, including monthly and/or annual maximums may apply. Patient is responsible for any costs once program limit is reached. Program not valid (i) if prescription for PYZCHIVA is paid, in whole or in part, under Medicare (including Part D, even in the coverage gap), Medicaid, Medigap, TRICARE, VA, DoD, or any other federal or state health care program, (ii) where patient is not using insurance coverage at all, (iii) where the patient's insurance plan reimburses for the entire cost of the drug, or (iv) where product is not covered by patient's insurance. The value of this program is exclusively for the benefit of patients and is intended to be credited towards patient out-of-pocket obligations and maximums, including applicable co-payments, coinsurance, and deductibles. It is a violation of the terms and conditions of this program to use it to enroll patients for the purposes of a copay accumulator or maximizer program. Sandoz reserves the right to take any appropriate action against any person or entity using the program in violation of the terms and conditions. Program is not valid where prohibited by law. Patient may not seek reimbursement for the value received from this program from other parties, including any health insurance program or plan, flexible spending account, or health care savings account. Patient is responsible for complying with any applicable limitations and requirements of their health plan related to the use of the Program. Valid only in the United States and US Territories (Puerto Rico, Guam, Northern Mariana Islands, and Virgin Islands). This Program is not health insurance. Program may not be combined with any third-party rebate, coupon, or offer. Proof of purchase may be required. Co-pay program has no cash value. Additional terms and conditions may apply. Sandoz reserves the right to rescind, revoke, or amend the Program and discontinue support at any time without notice.
If you don’t qualify for the Co-pay Program, Sandoz One Source may be able to connect you to other opportunities for financial support.
PYZCHIVA is brought to you by Sandoz, a company with 25+ years of experience in biosimilars. Sandoz was the first company to have an FDA-approved biosimilar in the US and currently has more than 10 FDA-approved biosimilar medicines.
Do not take PYZCHIVA if you are allergic to ustekinumab or any of the ingredients in PYZCHIVA.
PYZCHIVA is a prescription medicine that affects your immune system. PYZCHIVA can increase your risk of having serious side effects, including:
Serious Infections: PYZCHIVA may lower your ability to fight infections and may increase your risk of infections. Some people have serious infections while taking PYZCHIVA, including tuberculosis (TB), and infections caused by bacteria, fungi, or viruses. Some people have to be hospitalized for treatment of their infection.
You should not start taking PYZCHIVA if you have any kind of infection unless your doctor says it is okay.
Before starting PYZCHIVA, tell your doctor if you:
think you have an infection or have symptoms of an infection such as:
After starting PYZCHIVA, call your doctor right away if you have any symptoms of an infection (see above). These may be signs of infections such as chest infections, or skin infections or shingles that could have serious complications. PYZCHIVA can make you more likely to get infections or make an infection that you have worse. People who have a genetic problem where the body does not make any of the proteins interleukin 12 (IL-12) and interleukin 23 (IL-23) are at a higher risk for certain serious infections. These infections can spread throughout the body and cause death. People who take PYZCHIVA may also be more likely to get these infections.
Cancers: PYZCHIVA may decrease the activity of your immune system and increase your risk for certain types of cancers. Tell your doctor if you have ever had any type of cancer. Some people who are receiving PYZCHIVA and have risk factors for skin cancer have developed certain types of skin cancers. Tell your doctor if you develop any new skin growths.
Posterior Reversible Encephalopathy Syndrome (PRES): PRES is a rare condition that affects the brain and can cause death. The cause of PRES is not known. If PRES is found early and treated, most people recover. Tell your doctor right away if you have any new or worsening medical problems including headache, seizures, confusion, or vision problems.
Serious Allergic Reactions: Serious allergic reactions can occur. Stop using PYZCHIVA and get medical help right away if you have any symptoms of a serious allergic reaction such as feeling faint, swelling of your face, eyelids, tongue, or throat, chest tightness, or skin rash.
Lung Inflammation: Cases of lung inflammation have happened in some people who receive PYZCHIVA and may be serious. These lung problems may need to be treated in a hospital. Tell your doctor right away if you develop shortness of breath or a cough that doesn’t go away during treatment with PYZCHIVA.
Before you receive PYZCHIVA, tell your doctor about all of your medical conditions, including if you:
Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
Know the medicines you take. Keep a list of them to show your doctor and pharmacist when you get a new medicine.
When prescribed PYZCHIVA:
Keep PYZCHIVA and all medicines out of the reach of children.
Common side effects for PYZCHIVA include nasal congestion, sore throat, and runny nose; upper respiratory infections; fever; headache; tiredness; itching; nausea and vomiting; redness at the injection site; vaginal yeast infections; urinary tract infections; sinus infection; bronchitis; diarrhea; stomach pain; and joint pain. These are not all of the possible side effects with PYZCHIVA. Tell your doctor about any side effect that you experience. Ask your doctor or pharmacist for more information.
Please see your doctor to discuss any questions you may have.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-8​0​0-FDA-1​0​8​8.
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